Research Interests


My work focuses both on the mathematical theory for singularly perturbed dynamical systems and on applications to problems arising in pattern formation, fluid mechanics, systems of mechanical oscillators, and neurophysiology.

Pattern formation in chemistry

(Joint work with Arjen Doelman, Wiktor Eckhaus, Rob Gardner, Paul Zegeling)
Over the past 25 years, the field of pattern formation has undergone a revolution fueled by experiments in chemistry and fluid mechanics. Perhaps one of the most intriguing outstanding questions is to understand the phenomena of self-replicating spots and pulses, which were discovered in 1993 on the Gray-Scott model by J. Pearson and H. Swinney. Spots and pulses are regions of high activator and low inhibitor concentration. In these autocatalytic reactions, the spots and pulses can shrink, grow, oscillate in size, and even self- replicate, depending on the rate at which the inhibitor is supplied to the reactor, on the rate at which the activator decays, and on the relative diffusivities. Visually, self- replication looks much like cell reproduction: a spot enlarges, its length growing perpendicular to the direction of its motion, and then pinches into two. Mathematically, the Gray-Scott model consists of a pair of coupled reaction-diffusion equations. My collaborators and I establish the existence and stability of pulses. This analysis identifies the regimes in which stationary and slowly-modulating pulses are observed, and it establishes the boundaries (both external and internal) of the self-replication regime. In addition, we identify the mechanism in 1-D by which a one-pulse solution splits into a two-pulse solution, which is the fundamental event during self-replication, and show that there is a large class of coupled reaction-diffusion equations that exhibit the same type of phenomena as the Gray-Scott model does. Finally, with a Ph.D. advisee of mine, D. Morgan, we prove the existence and stability of spatially-periodic patterns that are the attractors in the self-replication regime.

Pattern formation in bacterial colonies


Jointly with our Ph.D. thesis advisee G. Medvedev, N. Kopell and I have investigated the periodic-terracing of Proteus mirabilis bacteria observed in experiments by J. Shapiro of the University of Chicago. This fascinating phenomena involves the dynamics of single-cell and multi-cellular forms of the bacteria, and the collective evolution of the colony as it alternately expands and consolidates. We identify waves of diffusivity as being essential switching mechanisms from the consolidation phase to the expansion/swarming phase.

Bubble dynamics


Applications of existing dynamical systems techniques and the development of new ones for problems in fluid mechanics has been another ongoing theme. Jointly with A. Harkin and A. Nadim, we study gas bubbles in liquids, focusing in particular on the acoustic cavitation of bubbles and on the nonlinear interactions of bubbles in small clusters. Cavitation occurs when bubbles expand and pop in response to changes in the ambient acoustic pressure. We have taken one of the first steps beyond the 50-year-old quasistatic criterion for cavitation and developed a criterion for the onset of dynamic cavitation, which occurs when the external pressure changes on the same time scale as that of the natural breathing oscillations, for slightly subcritical bubbles. Presently, we are investigating the coupled oscillations of two bubbles and the nonlinear interactions between shape and breathing modes. In both cases, there are resonant and nonresonant mechanisms for energy transfer, and we endeavor to find thresholds for them.

Mathematical theory for singularly perturbed systems


Singularly perturbed systems have a rich geometry, and the overarching goal of my work has been to uncover and exploit it. Work of my first Ph.D. student, C. Soto-Trevino (1997), develops a geometric method to prove the existence of periodic orbits in these systems. I have also helped to develop, with C. Jones and N. Kopell, the exchange lemma, which is a major theoretical tool for tracking invariant manifolds in singularly perturbed systems. In addition, I have analyzed applications to resonant dynamics in various N-degree- of-freedom Hamiltonian systems (with G. Kovacic), to rapid oscillations in coupled mechanical oscillators (with S. Weibel and J. Baillieul), and to 2-point boundary value problems (with M. Hayes and N. Kopell).

Adiabatic Hamiltonian systems


Separatrix-swept regimes are the regimes complementary to those in which the famous theory of adiabatic invariants (discovered by Einstein and Alfven) applies. I discovered numerically (and analyzed mathematically) the rich structure of the homoclinic tangles responsible for chaos in these systems. I have also focused on a number of applications in fluid mechanics of the mathematical theory for these systems: to develop a mixing theory for low Reynolds number flows and to develop a scattering theory for oceanic internal waves.

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